Need some advise on how to use a RESTful API

I need to work on a django app that will eventually benefit from a RESTful API so it can be used from any web browser as well a from apps writtens for iOS and Android.

Being so new to django development I don't even have any ideas on how to use a RESTful API, for example,

1. Should I begin the development use a RESTful API, or should I add ir when needed? ( it IS going to be used anyways)
2. Of course I understand I'm adding another layer of work to the final product but, can someone please explain how bad deep and how complicated this layer might be?
3. I've found a couple of online tutorials and I'll soon be working on them, but I honestly think there is nothing quite like reading the opinions of different people as to what the workflow with a RESTful API in django implies. I think a simple overview of the general workflow will answer most of the questions I have in mind right now.

Thanks a lot in advanced!

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